The 2024–25 CAF Champions League group stage began on 26 November 2024 and ended on 19 January 2025. 16 teams competed in the group stage to decide the eight places in the knockout stage of the 2024–25 CAF Champions League.
The teams were seeded by their performances in the CAF competitions for the previous five seasons (CAF 5-year ranking points shown next to every team). Each group contained one team from each of Pot 1, Pot 2, Pot 3, and Pot 4, and each team were allocated to the positions in their group according to their pot.
In the group stage, each group was played on a home-and-away round-robin basis. The winners and runners-up of each group advanced to the quarter-finals of the knockout stage.
The teams were ranked according to points (3 points for a win, 1 point for a draw, 0 points for a loss). If tied on points, tiebreakers were applied in the following order (Regulations III. 20 & 21):
Goals scored in head-to-head matches among tied teams;
Away goals scored in head-to-head matches among tied teams;
If more than two teams were tied, and after applying all head-to-head criteria above, a subset of teams was still tied, all head-to-head criteria above were reapplied exclusively to this subset of teams;
^The Al Ahly v CR Belouizdad match, originally scheduled to be played on 13 or 14 December, was rescheduled to be played on 22 December 2024 due to Al Ahly participation in the 2024 FIFA Intercontinental Cup.